SPL RF May 2022

EN_01523467_1462

30,00 EUR Private use
Making print for private purpose, storage in computer memory, no distribution rights.
40,00 EUR Internet - private use
Strictly for editorial, single use on a personal (nonprofit) web site, Internet portal, social media (Facebook, Instagram etc.), blog for 1 year. Not for resale. Maximum picture size 2000px.
75,00 EUR Internet commercial use
Strictly for editorial, single use on a commercial web site, Internet portal, social media (Facebook, Instagram etc.), blog for 1 year. Not for resale. Maximum picture size 2000px.
90,00 EUR Print use
Strictly for editorial, single use, inside of newspaper, magazine, book (including digital version), one edition, one single country. Not for resale.

Gross prices

special instructions

Internet +100%

caption

Molecular model of the disruptor of telomeric silencing 1-like (DOT1L, mid blue) protein complexed with a histone (dark blue). Histones are proteins that DNA (deoxyribonucleic acid) wraps around before being packaged into chromosomes. DOT1L transfers a methyl group to a lysine amino acid residue on the histone, a process known as methylation. This transfer can only occur if the protein ubiquitin (light blue) has already bound to the histone. Histone methylation can activate or repress the transcription of genes without changing the actual genetic sequence and so is an example of an epigenetic change.

headline SPL RF May 2022

created date 2022-05-07

credit JUAN GAERTNER/Science Photo Library RF/East News

source Science Photo Library RF

byline JUAN GAERTNER

original transmission reference f0357250

weight 13,32MB

size 58cm x 43cm by 300dpi

keywords - Show

2022, ACID, AGING, AMINO, ARTWORK, BIOCHEMICAL, BIOCHEMISTRY, BIOLOGICAL, BIOLOGY, CARCINOGENESIS, CGI, CHROMATIN, COMPLEX, COMPLEXED, CYTOSINE, DEOXYRIBONUCLEIC, DIGITALLY-GENERATED, DNA, dot1-like, dot1l, ENZYME, EPIGENETIC, EPIGENETICS, EXPRESSION, GAERTNER, GENE, GENETICS, GENOME, GROUP, h3k79, HISTONE, ILLUSTRATION, JUAN, LYSINE, MAY, METHIONINE, METHYL, METHYLATION, methyltansferase, METHYLTRANSFERASE, MODEL, MODIFICATION, MOLECULAR, MOLECULE, NO-ONE, NOBODY, PROMOTOR, PROTEIN, REGULATION, RF, S-ADENOSYL, SPL, STRAND, SUPPRESSION, TRANSCRIPTION, TUMOR, UBIQUITIN, ubiquitinated, UBIQUITINATION,