Vytorin 10/20 ( 10mg ezetimibe and 20mg simvastatin) is a combination drug which is used to reduce the total amounts of cholesterol, LDL (bad) cholesterol, triglycerides (another type of fat), and apolipoprotein B (a protein needed to make cholesterol) in the blood. Ezetimibe and simvastatin is also used to increase the level of HDL (good) cholesterol in the blood. Recent studies have found that it may possibly increase the risk of cancer in patients who are taking it.