Illustration of the TNM staging of prostate cancer. T1 and T2 : cancer localised in the prostate and not spreading beyond the capsule (absence of infected lymph nodes, absence of metastasis). T1 : histological diagnosis only (not visible on medical imaging and cannot be palpated). T2 : palpable during a digital rectal examination. T3 : spreading of the cancer to surrounding tissue (spreading through the prostatic capsule) T4 : spreading to adjacent organs (bladder, rectum, pelvic floor).