Internet +100%
SPECIAL RATES FOR EDITORIAL AND BOOKS
RF RATES FOR OTHER USE
Illustration of engineered receptors (light blue) on the surface of a T-lymphocyte bind specifically to CD19-antigen molecules (red) on a leukemia cell. This activates a signal cascade in the T-cell leading to the segregation of vesicles that contain perforin and granzyme. The perforins build channels for the granzymes which enter the leukemia cell and activate finally the apoptosis (cell death) of the cancer cell.